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Health Features - Premarin
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What is Premarin?
Premarin is an organic hormone replacement pill manufactured from the oestrogen extracted from the urine of pregnant mares. In order to collect this urine the maresPhoto supplied by premarin.org are tethered in stalls (front and back) for the period of their pregnancy, this is generally for 6mths of their pregnancy but can be up to 11mths of the year in the less scrupulous farms.
 
There is a voluntary code for exercise, "as required'. This may or may not be adhered to, and of course it is up to the PMU farmer to decide what 'as required' means, at best it may mean a few hours offline every 3 or 4 days. These stalls are often just 8 feet long, by 3 1/2 feet wide and some are just 5 feet high!  If the tethers are too short the mare may be unable to lie down.
 
In the past, it was commonly reported that water was restricted in order to increase the concentration of oestrogens by volume of urine and thereby reduce shipping costs. The pharmaceutical company now claims that the water restriction policy has been modified
 
Mares unable to conceive quickly, are slaughtered, as are most of the foals. The figures on foal slaughter are often concealed by the numbers which are sold through premarin sales.  In truth these foals are mainly purchased by slaughter houses.  The normal life of a healthy horse is 20 to 30 years,  but most of the Premarin mares will become worn out after 7 or 8 years, filly foals not slaughtered may be brought 'on-line' at just 18mths.   The latest figures gathered by Horse-Aid showed approx. 439 PMU (Pregnant Mares Urine) farms in existence in Canada and the U.S.  That means that  the total number of mares, replacement mares, stallions, and PMU foals adversely impacted by PMU production is estimated by HorseAid to be at well over 100,000 per year. 

Wyeth-Ayerst Laboratories are the only pharmaceutical company which manufactures this product (of American Home Products' 1998 net sales of 13.5 billion dollars world-wide, sales of Wyeth's Premarin based drugs, including Prempro, Premphase, and Prempac, accounted for 1.6 billion dollars). 

Ayerogen; Ayerogen Crema Vaginal; Azumon; C.E.S.; Climarest; Conjugated Estrogens; Conjugen; Dagynil; Emopremarin; Equin; Femavit; Hyphorin; Mannest; Menopak-E; Menpoz; Neo-Menovar; Oestro-Feminal; Ovest; Premaril; Premarin; Premarin Crema V; Premarin Creme; Premarin Vaginal Creme; Premarina; Premarose; Presomen; Prevagin-Premaril; Romeda; Sefac; Srogen; Sukingpo; Transannon, Prempro, Premphase, and Prempac

Premarin has been in production since 1942, however there is no better time to campaign to have this product banned.
 
Synthetic alternatives are a relatively recent development
 
HRT\Premarin has shown up in many studies recently as a women's health risk
 
The use of HRT is rising dramatically as 'baby boomers' mature and demand HRT making Premarin the top perscribed drug in the United States.  TOP 200 LIST
 
There is a considerable body of opinion currently that the PMU industry has cleaned up its act in the last few years.  There is no evidence to support this and although many 'tours' are sited, these are often strictly controlled with the visitors being directed to specific 'show' farms.

 

Important Update !!!
 
Sales of Premarin have been dropping dramatically due to the increased publicity about the health risks of HRT.  This is good news in the long term for horse welfare but in the short term may mean that Wyeth may order the slaughter of thousands of mares in an attempt to 'down-size' their production by 1/3.
 

 
The Arguments for keeping Premarin farms
 
Many advocates will try to tell you the benefits of HRT, that women will 'die' or be in considerable difficulties without HRT,what a terrible thing Osteoporosis is, or that all of the horses will be killed if the Premarin industry is suddenly closed down.  All of these arguments are factually and logically flawed, so lets take a look at them.
 
1. The numbers of women who have medical needs for HRT is much lower than the number of women who are taking HRT for cosmetic or 'marketing' reasons.  However, that aside, Premarin is only one drug for HRT there are many others. Obviously there are some women for whom there is a sound medical reason for HRT.  Those who have had hysterectomies for example - stopping the production of Premarin will only require a change in drug not the ceasation of HRT. (see are there alternatives?)
 
2. Osteoporosis is not a natural consequence of aging, its is mainly a consequence of poor nutrition and lack of exercise.  HRT is a 'quick fix' solution offered by doctors rather than sending patients out to get more weight bearing exercise and eat better (although again there will be numbers of women for whom HRT is required and this can be provided by non-Premarin based drugs) see Osteoporosis links
 
3. All the horses will not be killed immediately. Regulatory changes to industries take place over a period of years.  During this time the horses could be sold or slaughtered.  However, they are slaughtered now so it really makes little difference to the current horses - stopping the manufacture of Premarin would stop the slaughter of more horses in the long term.  Its also interesting that the people who bring up this argument are often the same people who tell you that horses used for Premarin are not slaughtered, they are sold to nice homes and breed sporthorses - if this is the case there's no logic that says these farmers can't continue to do that.
YES!  There are synthetic, FDA-approved alternatives; Ogen, Estrace, Estradiol Transdermal System, Estradiol tablets, Estropipate, Estrone, and Meneste, and Cenestin, to name a few.  Premarin and its derivatives are over 50 years old.  Many older drugs carry more risks and have more side-effects than newer versions - see womens health issues
 
Recent trials of soy products for hormone replacement have also shown good results, so there is little excuse to continue this cruel treatment of tens of thousands of mares and the slaughter of their foals.
 
More importantly there are considerable doubts and concerns being raised about Hormone Replacement Therapies in general and Premarin in particular that you should make yourself aware of before being duped by the marketing hype surrounding menopause and HRT. 
 

Although all PMU farms are in Canada or North America there are still things you can do to help stop this abuse of horses.
 
If you (or someone you know) are currently using HRT ask your doctor NOT to prescribe Premarin, ask for a synthetic alternative.  ALL Premarin is currently organic, and ALL organic Premarin is derived from oestrogens extracted from Pregnant Mares' Urine.
 

STOP!    buying the following products from American Home Products or their Animal Health Products subsidiary Fort Dodge (there are plenty of alternatives for each) 


Advil, Ancin, Caltrate Plus (calcium supplement),
Centrum (vitamins), Chap Stick (lip balm), Clearblue Easy (pregnancy test)  Denorex (shampoo), Dimetap (cold medicine), Dristran, Preparation H, Primatene (asthma relief), Robitussin (cough medicine),
 
Fort Dodge Animal Health Products - Quest horse dewormer , sold here as Equest and Cydectin
On This Page
 
Related Pages
Premarin H&P Letter

PETA Guide to effective letter writing


WRITE to the government agencies listed below protesting the import and funding of Premarin and demanding that information regarding the manufacture of pharmaceuticals be freely available to all end users, so that they can make informed decisions about their role in animal abuse.
 

Pharmac (approves/funds prescription drugs in New Zealand) Freepost 4072, Box 10-254, Wellington, NEW ZEALAND    (no stamp required within New Zealand)

Minister of Health & Racing: Annette King c:\- Parliament or email: aking@ministers.govt.nz

Ministry of Health: P.O. Box 5013, Wellington, New Zealand.   Email: EmailMOH@moh.govt.nz

 

Write to the manufacturers and their subsidiaries, protesting the manufacture of Premarin and advising them of your boycott of their products.
 

Fort Dodge N.Z. Limited, Private Bag 92903, Onehunga.  Auckland

Wyeth-Ayerst Laboratories, PO Box 8299, Philadelphia, PA 19101

The Canadian Ambassador (most PMU farms are in Canada)

 
Write to those people who advertise products associated with any of the Wyeth-Ayerst Labs and its subsidiaries and ask if they are aware of the Premarin issue.

These could include - Monty Roberts (who endorses Quest), Horse & Pony Magazine (Who advertises Equest), Susan Devoy\Bernice Mene who advertise Centrum Vitamins


Let all your friends know about Premarin and encourage them to do the same!


 
 

 

 
 
If you wish to see whether this drug is sold in your Country RXLIST

 

Pro-Premarin Farming Information
 
NAERIC - The North American Equine Ranching Information Council - this is the official industry site for the PMU farmers, so there are lots of lovely soft focus photos of blonde women and horses but even it confirms the size of the stalls the horses are kept in.

 

 

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